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Research Associate in Cancer Biology

Department
Biology
Based at
University of York
Hours of work
Full-time
Contract status
Fixed term
Salary
32,817 - 40,322 per year
Posted Date
03/06/2021
Apply by
23/06/2021
Job Reference
9459

Role Description

Department

We are looking for talented and motivated full-time Postdoctoral Research Associates to join the group of Professor Ian Hitchcock based in the Department of Biology at the University of York. The Hitchcock lab focuses on understanding the mechanisms of cytokine signalling in haematological malignancies with particular interest in translating fundamental biology to address therapeutic needs. We have recently taken a multi-disciplinary approach to characterise the mechanisms of cytokine receptor activation in myeloproliferative neoplasms (Wilmes et al., Science 2020; Sangkhae et al., Blood, 2014) and modify cytokine signalling to direct haematopoietic cell fate outcomes (Cui et al., PNAS, 2021).

The posts are funded by Cancer Research UK and industrial partners. These posts are full time, on a fixed term basis for 18 months (with a possible extension) or 30 months (with a possible extension). This is a grade 6 post, with salary in the range £32,817 - £40,322 per year depending on experience.

Role

We currently have two posts available; one focused on further understanding the mechanisms of oncogenic cytokine signalling in haematological malignancies and the other working with an industrial partner to exploit these findings to identify targets for potential clinical translation. The successful candidates will benefit from highly productive interactions with academic and industrial collaborators in the UK, Europe and USA around the themes of haematology, haematopoietic stem cells, cytokine receptor biology, signal transduction and high throughput assay development. Both post holders will be expected to drive their independent projects, but also work closely with each other and with other lab members and assist in the identification and development of potential new areas of research.

Opportunities for mentorship and additional collaborations will be available and encouraged

Skills, Experience & Qualification needed

  • The successful candidates will have a PhD in a biomedical sciences discipline or equivalent experience in haematology, immunology or cancer cell biology, with specific expertise in cell and molecular biology, cell line assay development, molecular cloning and primary cell isolation and culture
  • knowledge of a range of research techniques and methodologies as well as additional expertise in flow cytometry, microscopy and mouse models would be advantageous
  • The successful candidate must have experience of carrying out both independent and collaborative research, writing up research work for publication and a willingness to contribute to the process of securing future research funding.

Interview date: W/C 12 July exact date TBC 

For informal enquiries: Please contact Professor Ian Hitchcock (ian.hitchcock@york.ac.uk)

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