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Research Associate in Population Genomics

Department
Biology
Based at
University of York - Heslington Campus
Hours of work
Full-time
Contract status
Fixed term
Salary
32,817 - 40,322 a year
Posted Date
15/09/2020
Apply by
15/10/2020
Job Reference
8756
Documents

Role Description

Department

The Department of Biology has a research portfolio that spans ecology to structural biology. The Department’s research has been judged world leading in biochemistry, chronic disease, microbiology, plant biology and ecology. Following the 2014 REF the Department of Biology at York was again placed in the Top 10 in the UK. It is 1st for impact outside academia - our research has had major influence on environmental policy, industry and health.

The York Biomedical Research Institute (YBRI) is a virtual institute that brings together researchers across the biomedical research spectrum with research ranging from fundamental studies on immunology, haematology, microbiology and parasitology to first-in-human and other early phase clinical research. Our aim is to develop a greater understanding of the processes underlying chronic infectious and non-infectious disease, and thus to develop new approaches to prevention and treatment.

We are looking to recruit a highly-motivated Research Associate to conduct research on Leishmania population genomics under the supervision of Dr. Daniel Jeffares. This position will involve collection and analysis of population genomic sequence data from Leishmania parasites with partners in Sudan, Ethiopia, Uganda and Kenya to describe population demographics and evolutionary history of L. donovani and the effects of parasite genetic variation on immune responses, treatment efficacy and disease outcome. Genomic data will be analysed in combination with detailed immunology data in collaboration with the PREV_PKDL project (https://www.prevpkdl.eu/). This project will be collaborate with Prof. Paul Kaye and be supported by world-leading expertise in Leishmania cell biology, immunology and genomics at YBRI.

Role

  • To conduct individual and collaborative research under the supervision of Daniel Jeffares and to contribute to the production of research.  Duties to include: sample preparation/QC for genome sequencing; data archiving and sample management; computational data analysis and interpretation of research data; use of appropriate research techniques and methods; writing up of research results and dissemination through publications, seminar and conference presentations and public engagement and outreach activities; contributions to student supervision and training; contributing to the identification of possible new areas of research
  • To assist in the identification and development of potential areas of research and the development of proposals for independent or collaborative research projects
  • To participate actively in the planning and management of research projects, including supervising the work of others, providing expert advice and guidance, and assisting with undergraduate teaching in own area of expertise where required

Skills, Experience & Qualification needed

  • You will already possess a PhD in population genetics, genomics or related science.
  • Knowledge of population genomics or quantitative genetics is essential.
  • Competency with computational sequence analysis and scripting is essential.
  • You will have experience with analysis of next-generation sequence data.
  • Experience with preparing manuscripts for publication is desirable.
  • Experience with protozoan parasitology is desirable.
  • Knowledge of immunology would be an advantage, but is not essential.

Interview date: TBC

For informal enquiries: please contact please contact Daniel Jeffares on daniel.jeffares@york.ac.ukor alternatively contact the Biology DMT Hub on biol-dmthub@york.ac.uk

This post is available on a fixed term basis until 31 December 2023.

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 A place where we can ALL be ourselves #EqualityatYork

 

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