Postdoctoral Research Associate in Chemical Biology

Role Description

Department

Applications are invited for a Postdoctoral Research Associate to join the group of Dr Lianne Willems (https://www.york.ac.uk/chemistry/staff/academic/t-z/lwillems/) in the Department of Chemistry at the University of York. The Willems group has a particular interest in the study of glycans and carbohydrate-active enzymes in relation to human disease. Supported by the Department’s research strengths in Chemical and Structural Biology, you will be involved in cutting-edge research in the field of chemical glycobiology. The goal of this project is to develop cell-based assays to study the function of a set of enzymes involved in glycan biosynthesis, aiming to gain novel insights into the roles these proteins play in disease pathology.

The Department of Chemistry is one of the UK's leading Chemistry departments and is renowned internationally for our research. We strive to provide a working environment which allows all staff and students to contribute fully, to flourish, and to excel. We have been recognised consistently for our family-friendly policies and are proud of our Athena SWAN Gold Award.

Role

The purpose of this post is to conduct research to develop novel methodology to enable the manipulation and monitoring of a set of glycosyltransferases and corresponding cell-surface glycans in human cell lines. You will make use of genetic techniques as well as chemical tools developed by other lab members. Working both individually and collaboratively as part of multidisciplinary teams, the position offers the opportunity to advance your knowledge and skills in a variety of chemical biology approaches. You will provide guidance and support to other lab members as required and will contribute to the dissemination of research data through publications, presentations and outreach activities. The role will also involve some organisational and administrative activities connected to the research project and, where appropriate, assisting with the development of new research projects and proposals.

The post is available full-time with flexibility for up to 48 months

Skills, Experience & Qualification needed

• A first degree and a PhD or equivalent experience in a relevant sub-discipline of Chemistry (e.g. Chemical Biology) or Biomedical Sciences/Cell Biology
• Knowledge of cell biology and modern chemical biology approaches
• Knowledge and experience of a range of biochemical and molecular/cell biology techniques and methodologies
• Highly developed communication skills, both orally and in writing, and experience with the writing of journal publications
• Experience/competency to carry out both individual and collaborative research projects, working as part of a team or independently using own initiative; including the ability to develop research objectives and to plan and prioritise own work
• Highly motivated and professional work ethic, with commitment to high quality research and personal development, a collaborative ethos and a willingness to proactively support colleagues and students
• Enthusiasm for the specific subject matter of the project

Interview date: 28 January 2020

For informal enquiries: please contact Dr Lianne Willems (lianne.willems@york.ac.uk)

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