Skip to content

Research Associate in Malignant Blood Stem Biology

Department
Biology
Based at
University of York - Heslington Campus
Hours of work
Full-time
Contract status
Fixed term
Salary
32,236 - 39,609 a year
Posted Date
08/07/2019
Apply by
06/08/2019
Job Reference
7820
Documents

Role Description

We are looking for a highly qualified full-time Postdoctoral Research Associate to join the group of Dr David Kent based in the Department of Biology at the University of York.

The Kent laboratory's research focuses on understanding cell fate decisions in normal and malignant blood stem cells. We have recently pioneered approaches in single cell biology which link single stem cell function to single cell gene expression (Wilson et al, Cell Stem Cell; Nestorowa et al., Blood; Shepherd et al., Blood 2018) and determined that the order of mutation acquisition impacts disease evolution and clinical features of blood cancers (Ortmann et al., NEJM).

The position will explore malignant stem cells with Tet2 mutations to understand disease evolution and stem cell expansion. As the successful candidate, you will join an existing project studying the role of Tet2 in mouse and human blood stem cells. You will drive an independent project but also work closely with other lab members. You will also assist in the identification and development of potential areas of research and the development of proposals for independent or collaborative research projects as well as write up research results for dissemination through publications, seminar and conference presentations and public engagement and outreach activities. Opportunities for mentorship and additional collaborations will be available and encouraged.

The successful candidate must hold a PhD or equivalent research experience in mouse stem cell biology with specific expertise in single stem isolation and culture, mouse models, bone marrow transplantation and macrophage biology. Additional knowledge of stem cells from other tissues and flow cytometry would be advantageous. They must have prior research experience involving blood stem cells and in using mouse models. Experience of studying Tet2 and inflammation would be particularly advantageous. They will have demonstrable research experience and will have presented their research at international conferences.

This position is funded by ERC.

The post is full-time, fixed term for 2 years and salary will be in the range £32,236 - £39,609 per annum.

Informal enquiries are welcomed and should be made to Dr. David Kent via email: david.kent@york.ac.uk.  For an alternative contact, please email biol-dmthub@york.ac.uk.

For further information and to apply on-line, please click on the ‘Apply’ button above.

The University is committed to promoting a diverse and inclusive community  – a place where we can all be ourselves and succeed on merit. We offer a range of family friendly, inclusive employment policies, flexible working arrangements, staff engagement forums, campus facilities and services to support staff from different backgrounds.

Athena Gold 2017 

 A place where we can ALL be ourselves #EqualityatYork

 

Login

Forgot password | Register

Why York?

York is one of the most successful universities in the UK.

With world-class activity across the spectrum from the physical sciences, life sciences, and social sciences to the humanities, we have been recognised as one of the top 100 universities in the world, gaining outstanding results in official assessments of our research and teaching.