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Postdoctoral Research Associate in Glycoenzyme biocatalyst development

Department
Chemistry
Based at
University of York - Heslington Campus
Hours of work
Full-time
Contract status
Fixed term
Salary
32,236 a year
Posted Date
03/12/2018
Apply by
02/01/2019
Job Reference
7214
Documents

Role Description

Department

A fixed term postdoctoral appointment is available from January 2019 or as soon as possible thereafter for up to 15 months in the York Structural Biology Laboratory, part of the Department of Chemistry. You will work in the group of Dr Martin Fascione on a BBSRC funded IB Catalyst project.

The Department of Chemistry is one of the largest and most successful academic departments at York. The Department was placed in the top ten UK universities for Research Power by the 2014 Research Excellence Framework exercise (REF).  As a Department we strive to provide a working environment which allows all staff and students to contribute fully, to flourish, and to excel. We are proud of our Athena SWAN Gold Award.

Role

You will focus on developing a biocatalytic tool box to enable the chemo-enzymatic synthesis of glycans that contain natural and modified monosaccharides for application in glycan microarrays, and will involve molecular biology, scale up protein expression and purification and biochemical assay development. You will carry out research and will focus on developing a biocatalytic tool box to enable the chemo-enzymatic synthesis of glycans that contain natural and modified monosaccharides for application in glycan microarrays, and will involve molecular biology, scale up protein expression and purification and biochemical assay development.

Skills, Experience & Qualification needed

  • First degree in Chemistry or Biochemistry
  • PhD in biochemical glycoscience
  • Knowledge and experience of molecular cloning, recombinant protein expression in E. coli and protein purification and biochemical assays for the functional characterisation of glycoenzymes, including those active on galactose and nonulosonic acids
  • Demonstrable interest/experience in carbohydrate biochemistry, protein mass spectrometry, glycosyltransferases and bacterial glycans.
  • This position is funded as part of a consortium project so you require the ability to work both independently and as part of a larger team with members across other labs in the UK.
  • Excellent communication skills to engage effectively with a wide-ranging audience, both orally and in writing, using a range of media including publication in journals and delivery of presentations at conferences or exhibiting work at other events
  • Ability to plan and prioritise own work in order to meet deadlines, exhibiting self-initiative
  • Highly motivated and professional work ethic, with commitment to high quality, a collaborative ethos and a willingness to proactively support colleagues and students

Informal enquiries may be made to Dr Martin Fascione (martin.fascione@york.ac.uk).

The Department of Chemistry values all employees for the qualities and skills they bring to the workplace and aims to be a diverse and egalitarian community in which all can thrive.

The University is committed to promoting a diverse and inclusive community  – a place where we can all be ourselves and succeed on merit. We offer a range of family friendly, inclusive employment policies, flexible working arrangements, staff engagement forums, campus facilities and services to support staff from different backgrounds.

Athena Swan Gold 

 A place where we can ALL be ourselves #EqualityatYork

 

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