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Postdoctoral Research Associate in Chemical Biology

Based at
University of York - Heslington Campus
Hours of work
Contract status
Fixed term
31,604 - 38,832 a year
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Role Description

Postdoctoral Research Associate in Chemical Biology: The O-GIcNAc modification and beyond


A fixed term postdoctoral appointment is available (until 31st March 2021) in the York Structural Biology Laboratory, part of the Department of Chemistry, to work in the group of Professor Gideon Davies, FRS on a Royal Society-funded project on the enzymology, 3-D structure and chemical biology of the O-GlcNAc modification.

The Department of Chemistry is one of the largest and most successful academic departments at York. The Department was placed in the top ten UK universities for Research Power by the 2014 Research Excellence Framework exercise (REF).  As a Department we strive to provide a working environment which allows all staff and students to contribute fully, to flourish, and to excel. We are proud of our Athena SWAN Gold Award.

The University of York is a member of the Russell Group of research-intensive UK universities. The recent Research Excellence Framework (REF) confirmed the position of the University among the leading institutions in the UK for research.


You will conduct research on enzymology, 3-D structure and chemical biology of the O-GlcNAc modification under the supervision of senior colleagues. You will focus on protein-protein interaction studies, initiation of CryoEM analyses and enzyme characterisation. You will assist in the identification and development of potential areas of research and the development of proposals for independent or collaborative research projects.   You will need a good understanding of gene expression and protein production, chemical glycobiology, proteomics and either a good understanding or a strong desire to learn structural biology techniques including CryoEM. 

Skills, Experience & Qualifications needed

You are expected to have a first degree in Biochemistry, Cell Biology, Chemistry or a related discipline and a PhD in Enzymology, Cell Biology, Structural Biology, or equivalent experience. You will have a significant experience of gene expression and protein production as well as in aspects of enzymology (from, for example: CryoEM, X-ray, proteomics, photoaffinity cross-linking, protein-protein partner mapping).  You will have a good knowledge of modern chemical biology and carbohydrate (bio)chemistry/glycobiology and an enthusiasm for enzymology, 3-D structure, chemical biology and the project. You will need to be self-motivated with a strong work ethic, but also willing to work as part of a research team. You will need to have a passion for the scientific literature and for communicating your own science through publication and conference presentations.

You will also have:

•             Highly developed communication skills including competency to write publication quality manuscripts and make presentations at conferences

•             Ability and experience of developing research projects and objectives, conducting research projects and working in a harmonious team

The post is fixed-term for up to 29 months, and will be available from 1st November 2018 or as soon as possible thereafter.

Salary from £31,604 - £38,832 on grade 6 of the University’s salary scales.

Informal enquiries may be made to Prof Gideon Davies (

Closing date:    17 August 2018

Vacancy reference: 6858

The Department of Chemistry values all employees for the qualities and skills they bring to the workplace and aims to be a diverse and egalitarian community in which all can thrive.

The University is committed to promoting a diverse and inclusive community  – a place where we can all be ourselves and succeed on merit. We offer a range of family friendly, inclusive employment policies, flexible working arrangements, staff engagement forums, campus facilities and services to support staff from different backgrounds.

Athena Swan Gold 

 A place where we can ALL be ourselves #EqualityatYork



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