A fixed term postdoctoral appointment is available for 36 months in the York Structural Biology Laboratory, part of the Department of Chemistry, to work in the group of Professor Gideon Davies, FRS on a Leverhulme-Funded project on the metabolism of the sulfur-containing glycolipids.
The Department of Chemistry is one of the largest and most successful academic departments at York. The Department was placed in the top ten UK universities for Research Power by the 2014 Research Excellence Framework exercise (REF). As a Department we strive to provide a working environment which allows all staff and students to contribute fully, to flourish, and to excel. We are proud of our Athena SWAN Gold Award.
The University of York is a member of the Russell Group of research-intensive UK universities. The recent Research Excellence Framework (REF) confirmed the position of the University among the leading institutions in the UK for research. The proportion of research activity of world-leading, 4* status is among the highest of any UK university, and York is rated tenth out of 155 higher education institutions for the impact of its research.
You will dissect the metabolic pathways of the unusual sulfur containing glycolipid sulfoquinovose through individual and collaborative research projects. You will analyse and interpret research data notably through the cloning, expression and characterization of enzymes of the SQ degradation pathways. Appropriate research techniques and methods will include X-ray crystallographic analyses of enzyme structure, obtain ligand complexes, analysis of enzyme kinetics and development of activity-based probes to identify SQ pathways in environmental pathways. You will work closely with teams in Cardiff and Melbourne, Australia and help write-up and disseminate research results, coordinate joint publications and further contribute to the identification of possible new areas of research. You will be expected to participate in seminar and conference presentations and enjoy public engagement and outreach activities.
Skills, Experience & Qualification needed
You are expected to have a first degree in Biochemistry, Chemistry or a related discipline and an appropriate PhD in Structural Biology or equivalent experience. You will have a significant experience of gene cloning and protein production. You will be experienced in modern protein crystallography, with knowledge of the the CCP4 program suite. You will need to be self-motivated with a strong work ethic, but also willing to work as part of a research team. You will need to have a passion for the scientific literature and for communicating your own science through publication.
You will also have:
The post is fixed-term for an initial period of 36 months, with the possibility of extension, and will be available from 8th January 2018 or as soon as possible thereafter.
Salary from £31,604 - £38,832 on grade 6 of the University’s salary scales.
Informal enquiries may be made to Prof Gideon Davies (firstname.lastname@example.org).
Closing date:15 November 2017
Vacancy reference: 6103
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