Applications are invited for two Postdoctoral Researcher positions to work on the structural and chemical enzymology of the enzymes of glycobiology, in the domains of human genetic disease, cancer, viral invasion and bacterial pathogenesis. The work is funded by an ERC-Synergy grant to York, Barcelona and Leiden and is available for up to 36 months. You will be supervised by Professor Gideon Davies, FRS, and will work in the ERC-Synergy team in the York Structural Biology Laboratory, within Chemistry.
You will conduct research into gene expression and structural enzymology of carbohydrate-active enzymes. You will apply activity-based probes, and other chemical biology methods to key enzymes involved in human health. The ultimate goal is to apply activity-based proteomics methods, in collaboration with Leiden and Barcelona, to identify, image and disrupt key enzyme systems involved in human glycobiology.
To conduct research into the application of activity-based probes to the detection and analysis of carbohydrate-active enzymes featuring structural analysis of key enzyme targets. The two posts, between them, must cover the following areas:
Interview date: To be confirmed
For informal enquiries: please contact Prof Gideon Davies on gideon.davies@york.ac.uk
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